Search results for "action potential bursts"

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Burst analysis tool for developing neuronal networks exhibiting highly varying action potential dynamics

2012

In this paper we propose a firing statistics based neuronal network burst detection algorithm for neuronal networks exhibiting highly variable action potential dynamics. Electrical activity of neuronal networks is generally analyzed by the occurrences of spikes and bursts both in time and space. Commonly accepted analysis tools employ burst detection algorithms based on predefined criteria. However, maturing neuronal networks, such as those originating from human embryonic stem cells (hESC), exhibit highly variable network structure and time-varying dynamics. To explore the developing burst/spike activities of such networks, we propose a burst detection algorithm which utilizes the firing s…

Computer scienceNeuroscience (miscellaneous)Interval (mathematics)ta3112lcsh:RC321-57103 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicineMoving averageHistogramBiological neural networkMethods Articleburst analysislcsh:Neurosciences. Biological psychiatry. Neuropsychiatry030304 developmental biology0303 health sciencesspike trainsQuantitative Biology::Neurons and Cognitionmicroelectrode arrayMEAaction potential burstsdeveloping neuronal networksMultielectrode arrayhuman embryonic stem cellsPower (physics)nervous systemSkewnesshESCsSpike (software development)Biological systemNeuroscience030217 neurology & neurosurgeryNeuroscienceFrontiers in Computational Neuroscience
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Burst analysis tool for developing neuronal networks exhibiting highly varying action potential dynamics

2012

In this paper we propose a firing statistics based neuronal network burst detection algorithm for neuronal networks exhibiting highly variable action potential dynamics. Electrical activity of neuronal networks is generally analyzed by the occurrences of spikes and bursts both in time and space. Commonly accepted analysis tools employ burst detection algorithms based on predefined criteria. However, maturing neuronal networks, such as those originating from human embryonic stem cells (hESCs), exhibit highly variable network structure and time-varying dynamics. To explore the developing burst/spike activities of such networks, we propose a burst detection algorithm which utilizes the firing …

purskeanalyysispike trainsQuantitative Biology::Neurons and CognitiontoimintapotentiaalipurskeetMEAmicroelectrode arrayaction potential burstsdeveloping neuronal networksihmisalkion kantasoluhuman embryonic stem cellssoluttoimintapotentiaaliryhmätnervous systemhESCsmikroelektordihilakehittyvät hermoverkotburst analysis
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